WOLVERINE blend: what it contains and what is known
In short
WOLVERINE is a peptide blend sold online that sellers say contains BPC-157 and TB-500. We know of no published study of the product itself.
- The composition sellers declare is usually BPC-157 and TB-500 in a 1:1 ratio, for example 10 mg of each in a 20 mg vial. The content has not been tested by an independent laboratory, and a seller's declaration does not guarantee it [10]E, not peer-reviewed.
- In rats, the combination of BPC-157 and TB-500 gave no added benefit over either one alone [2]C.
- BPC-157 has only three small pilot studies in humans [3], and for TB-500 the FDA has found no human exposure data [6]regulator.
- Both declared substances are named in the Finnish medicines list, and in sport they are banned at all times [7, 8]regulator.
What is the WOLVERINE blend?
The WOLVERINE blend’s composition rests on sellers’ declarations. The content has not been tested by an independent laboratory [10]E, not peer-reviewed.
WOLVERINE is the name of a peptide blend sold online. On the product pages of six sellers (13 Oct 2026) all declared BPC-157 and TB-500 as the components. Three also gave the amounts, and all three gave a 1:1 ratio: 5 mg of each in a 10 mg vial and 10 mg of each in a 20 mg vial [10]E, not peer-reviewed. Sellers are not named or linked.
The components sellers declare are these two:
- BPC-157 is a synthetic peptide of 15 amino acids, originally isolated from gastric juice [3].
- TB-500 is, according to the FDA, a fragment of thymosin beta-4 [6]regulator. Full-length thymosin beta-4 is a different substance [5]A [6]regulator.
Fimea gives both as example names under which peptide products are sold online. Some such products are labelled "for research use only" [1]regulator. Blends in general: Peptide blends: what is in the vial and why the seller's label is not enough. All blends: Blends.
Evidence at a glance
Each cell gives the kind of study and its source. The letter is the evidence level, not the result. Rows on single components do not concern the WOLVERINE product.
| Claimed effect | Humans | Animals | Cells |
|---|---|---|---|
| The WOLVERINE blend itself | None known to us | None known to us | - |
| BPC-157 and TB-500 together | 4 patients with knee injections, no comparison group; not stated whether TB-500 was used [9]B | In rats no added benefit over either alone [2]C | - |
| BPC-157 (declared component) | Two-person intravenous safety pilot [4]B; three small pilot studies [3] | Tissue repair in animal models [3]C | - |
| TB-500 (declared component) | No human exposure data [6]regulator | In rats the repaired tendon withstood a higher load [2]C | - |
| Safety | No data on the blend; thymosin beta-4 (a different substance) was tolerated in a phase 1 trial [5]A | - | - |
"-" = no study on this.
Has the WOLVERINE blend been studied?
Not as far as we know (see In short above).
What is known about the single components
The results below concern single components, not the WOLVERINE product.
- BPC-157 and TB-500 together, in rats. In a rat study, the cut and repaired Achilles tendons of 32 rats were treated for four weeks with BPC-157, TB-500, their combination or nothing (8 rats per group). In the TB-500 group the tendon withstood a higher load before failing than in controls. The combination gave no added benefit over either substance alone. This is the only study we found in which the substances were given together, and it used injections into the abdominal cavity [2]C.
- Knee injections in humans. In a retrospective chart review from a single clinic, four patients had received knee injections of BPC-157 and thymosin beta-4 with no comparison group. The article does not say whether this was TB-500 [9]B.
- BPC-157 into a vein. In a two-person pilot study, markers of the heart, liver, kidneys, thyroid and blood glucose showed no changes, and no side effects were reported [4]B. A review notes that large, rigorous human trials are lacking [3].
- Thymosin beta-4. Full-length thymosin beta-4 was given intravenously to healthy volunteers in a phase 1 trial: 54 people received a single dose and 30 received repeated doses. Adverse events were mild to moderate. It is, however, not the same substance as TB-500 [5]A [6]regulator.
Evidence on single substances does not transfer to a blend. When the blend's actual content, amounts and purity have not been independently tested, nothing about its effects can be inferred from these studies.
Who studies the WOLVERINE blend?
No one that we know of has published research on this product (see above).
Who wrote this page: the editorial team
This page was written by the Molecular Recovery editorial team. The draft was made with the help of AI, and the claims were checked against the sources (AI policy). The page has not been medically reviewed. How we work: About us.
What side effects can the WOLVERINE blend have?
There are no data on the blend's harms, because the blend has not been studied. According to Fimea, there is no reliable information on the content, quality and safety of products sold as peptides, and their effect on the body may be unpredictable [1]regulator.
What users report. In the Reddit accounts we compiled (not research), 27 of 71 people (38%) reported some harm, most often: mood or anxiety (8, 11%), fatigue or lethargy (7, 10%) and sleep problems (5, 7%). People tend to post when something goes wrong, so this share does not tell how common harms are. The figures are about the WOLVERINE blend as sold or as the writer named it, not about its single substances, and the blend's contents were not verified. 27 people (38%) used other substances at the same time. The harms in detail: WOLVERINE blend user experiences.
Risks of the combination, based on the declared components
- The FDA says BPC-157 may carry a risk of immune reactions and that there is little or no safety information on it [6]regulator.
- For TB-500 the FDA has found no human exposure data, so its possible harms in humans are unknown [6]regulator.
- The small human studies of BPC-157 reported no side effects, but no large studies have been done [3].
- For injectable products, impurities such as endotoxins that end up in the product during manufacture raise the risk of serious health hazards [1]regulator.
The safety of using the two substances together has not been studied in controlled human trials [2]C [9]B. When the content and amounts have not been independently tested, the risks of the combination cannot be assessed. More: Side effects and safety.
WOLVERINE blend dosage in studies
There is no studied dose for the blend, and the ratio sellers declare has not been independently tested [10]E, not peer-reviewed. The only combination study was done in rats with injections into the abdominal cavity, and it is not a study of the WOLVERINE product [2]C. Study doses of single substances: BPC-157 and TB-500. They are not recommendations. The blend itself has no dose page of its own.
Is the WOLVERINE blend legal in Finland?
Both substances that sellers declare are named in the Finnish medicines list [7]regulator.
- Medicines list. In the Finnish medicines list (230/2025), BPC 157 and TB-500 are named in annex 1 A, which covers medicinal substance analogues and prohormones classified as medicines [7]regulator.
- Fimea warning, 29 June 2026. Fimea warned about injectable peptides bought online, giving BPC-157 and TB-500 as examples. Fimea advises not ordering injectable peptides from online shops or through social media, and buying medicines only from legal pharmacies. A "for research use only" label means the product is not intended for humans [1]regulator.
- United States. BPC-157 and TB-500 were in FDA category 2, meaning bulk drug substances for compounding that may present significant safety risks. The nominators have since withdrawn the nominations, and the FDA page still shows the risk descriptions [6]regulator.
- Import. Peptides and the law. Bringing them back from travel: Travelling with peptides.
This is not legal advice. Disclaimer.
Is the WOLVERINE blend doping?
Yes, if the vial holds what sellers declare. On the WADA 2026 Prohibited List, BPC-157 falls under class S0 (non-approved substances), and thymosin beta-4 and its derivatives, for example TB-500, under class S2. Both classes are prohibited at all times, including out of competition [8]regulator. In a blend, one prohibited component is enough.
How to assess a WOLVERINE product
A seller's declared composition does not tell the buyer which substances are actually in the vial, how much of each, or whether something else is in it. According to Fimea, an unauthorised product may contain a different substance than the packaging states [1]regulator.
A certificate of analysis (COA) for a blend should identify each component separately by mass spectrometry (MS), state the amount of each, and refer to the same batch as the vial being sold. The FDA also points to peptide-related impurities and difficulty characterising the active ingredient [6]regulator. For injectables, endotoxins are a particular risk [1]regulator. More: How to read a COA and check a test result.
FAQ
What does the WOLVERINE blend contain?
The composition sellers declare is usually BPC-157 and TB-500 in a 1:1 ratio, for example 10 mg of each in a 20 mg vial. The content has not been tested by an independent laboratory, and a seller's declaration does not guarantee it [10].
Has the WOLVERINE blend been studied?
Not as far as we know: we know of no published study of this product. A combination of BPC-157 and TB-500 has been studied in rats, but that is not the same as this product [2]C.
Does BPC-157 plus TB-500 work better than either alone?
Not in rats. In an Achilles tendon study the combination gave no added benefit over either substance alone [2]C. In humans we found only a series of four knee injection patients with no comparison group [9]B.
Is WOLVERINE legal in Finland?
Fimea warns against injectable peptides bought online, and BPC 157 and TB-500 are named in the medicines list [1, 7]regulator. The blend's actual content has not been independently tested. This is not legal advice.
Are BPC-157 and TB-500 banned in sport?
Yes. On the WADA list BPC-157 is in class S0 and TB-500 in class S2, and both are prohibited at all times [8]regulator.
What do users themselves report about the WOLVERINE blend?
In the Reddit accounts of 71 people we compiled (not research), 40 (56%) reported some benefit and 27 (38%) some harm. The accounts are self-selected and prove neither that it works nor that it is safe: WOLVERINE blend user experiences.
Read the research yourself: sources
Every source opens the original publication or the regulator's page. The level shows what the source itself reports.
- Fimea. Fimea warns: do not use injectable peptides purchased online (29 Jun 2026). Fimea regulator
- Biçer O, et al. Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study. Jt Dis Relat Surg. 2026;37:822-837. PMID 42542926 C
- McGuire FP, et al. Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing. Curr Rev Musculoskelet Med. 2025;18:611-619. PMID 40789979 (review)
- Lee E, Burgess K. Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study. Altern Ther Health Med. 2025;31:20-24. PMID 40131143 B
- Wang X, et al. A first-in-human, randomized, double-blind, single- and multiple-dose, phase I study of recombinant human thymosin beta4 in healthy Chinese volunteers. J Cell Mol Med. 2021;25:8222-8228. PMID 34346165 A
- U.S. Food and Drug Administration. Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks. FDA regulator
- Finland. Lääkeluettelo (Fimea medicines list), 230/2025, annex 1 A. Finlex regulator
- World Anti-Doping Agency. 2026 Prohibited List. WADA regulator
- Lee E, Padgett B. Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain. Altern Ther Health Med. 2021;27:8-13. PMID 34324435 B
- Seller product pages for WOLVERINE, 6 sellers, read 13 Oct 2026: all 6 declare BPC-157 and TB-500; the 3 that give amounts all declare a 1:1 ratio (5 + 5 mg in a 10 mg vial, 10 + 10 mg in a 20 mg vial). Sellers' own claims, not tested by an independent laboratory. Not linked: this site does not link to shops. E, not peer-reviewed
Study details checked in PubMed on 9 Oct 2026. Fimea, FDA, Finlex and WADA pages read on 15 Sep 2026. Seller product pages read on 13 Oct 2026; sellers are not named or linked.
Evidence levels: A = randomised human trial or meta-analysis · B = observational human study or case series · C = animal study · D = cell or laboratory study · E = not peer-reviewed · regulator = a regulator's assessment or decision, not research evidence. The marker official means official product information (summary of product characteristics or label); it is not research evidence. For a review, the level shows what kind of research the statement rests on. No level: statements that something has not been studied, reviews' interpretations, named hypotheses and the general rules in our certificate-of-analysis guide.
Content is general information about research, not medical advice. If you have symptoms, contact a healthcare professional.