Glossary
The site's texts link to these terms. The glossary has 34 terms so far and is being extended.
- Agonist
- A substance that binds to a receptor and activates it in the same way as the body's own signalling molecule. A GLP-1 receptor agonist, for example, mimics the GLP-1 hormone. The opposite is an antagonist, which blocks the receptor.
- Amino acid
- The building block of proteins and peptides. Human proteins use 20 common amino acids.
- Animal study
- A study in, for example, rats or mice. The result does not automatically apply to humans.
- Bacteriostatic water
- Sterile water with a small amount of benzyl alcohol to slow bacterial growth.
- Case series
- A description of a group of patients who received the same treatment, with no comparison group. It cannot show whether a change was caused by the treatment.
- Clinical trial phases 1-3
- Steps of human research: phase 1 safety in a small group, phase 2 effect and dose, phase 3 a large comparison.
- COA (certificate of analysis)
- A lab report stating what a sample contains and how pure it is.
- Conference abstract
- A short summary of a study presented at a scientific meeting. It is usually not peer-reviewed like a published article, and it gives few details of the methods.
- Endotoxin
- A contaminant derived from bacterial cell walls. Fimea says endotoxins in injectable products can cause serious harm. A product can be free of live microbes and still contain endotoxin.
- Evidence level (A-E)
- The site's mark after a source reference: A = randomised human trial or meta-analysis, B = observational human study or case series, C = animal study, D = cell or laboratory study, E = not peer-reviewed. In addition, "official" = official product information and "regulator" = a regulator's assessment or decision, not research evidence.
- Fimea
- The Finnish Medicines Agency, Finland's medicines regulator. It supervises medicines and grants national marketing authorisations.
- GLP-1
- A gut hormone (glucagon-like peptide 1) that raises insulin release and reduces appetite. Semaglutide and tirzepatide mimic its action.
- Half-life
- The time it takes for the level of a substance in the blood to fall by half.
- Hila
- The Pharmaceuticals Pricing Board. It decides whether a medicine is reimbursable and confirms its reasonable wholesale price.
- HPLC
- High-performance liquid chromatography. Measures purity: how much of a sample is one substance.
- In vitro
- An experiment in cells or tissue in a lab, not in a living organism.
- IU (international unit)
- A unit that describes a substance's biological effect rather than its weight. Oxytocin doses, for example, are given in units.
- Kanta
- Kanta services: Finland's national digital health services, which store e-prescriptions and patient records, for example.
- Kela
- The Social Insurance Institution of Finland. It runs Finnish social security, including the health insurance reimbursement of medicines.
- Lyophilisation (freeze-drying)
- A drying method in which a solution is frozen and the water is removed under low pressure. Peptides are often sold as a freeze-dried powder because they keep better dry than in solution.
- Marketing authorisation
- A regulator's permission to sell a product as a medicine. Research peptides usually do not have one.
- Medicines list (Fimea)
- Fimea's decision "List of substances used as medicines and substances regarded as medicines" (the latest in the Finnish Statute Book is 230/2025). Substances in annex 1 of the list are regulated as medicines in Finland, so they cannot be sold as food supplements.
- Microgram (µg, mcg)
- One thousandth of a milligram: 1 mg = 1000 µg. The abbreviations µg and mcg mean the same; the dose pages use µg and the calculator mcg. A milligram (mg) is a thousand times larger, so mixing up the units is a dangerous mistake.
- MS (mass spectrometry)
- Measures molecular mass. Tells whether the substance is the right substance.
- Novel food
- A food or ingredient that was not used for human consumption to a significant degree in the EU before 15 May 1997. Selling it requires an EU authorisation.
- Orphan medicine
- The EU's orphan designation is given to a medicine meant for a life-threatening or chronically debilitating condition that affects no more than 5 in 10,000 people in the EU. The designation is not a marketing authorisation: it only says the medicine is being developed for a rare disease.
- Peptide
- A short chain of amino acids. Where a peptide ends and a protein begins is a convention, often around 50 amino acids.
- Pharmacokinetics
- How the body absorbs a substance, distributes it to tissues, changes it and removes it.
- Placebo and placebo response
- A placebo looks like a treatment but contains no active substance. The placebo response is symptom relief that comes from expectations, the natural ups and downs of symptoms or something other than the substance itself.
- Preclinical study
- Cell and animal studies done before any human studies.
- Randomised controlled trial
- Participants are allocated by chance to the treatment being studied or to a comparison, such as placebo. The strongest way to separate the effect of a treatment from chance and expectations.
- Reconstitution
- Dissolving a dry powder in a liquid before use, for example a peptide powder in bacteriostatic water.
- U-100 syringe
- An insulin syringe whose scale shows 100 units per ml. The units measure volume, not the amount of substance.
- WADA and the Prohibited List
- The World Anti-Doping Agency. Its Prohibited List names the substances and methods banned in sport. The list is updated at least once a year: the new version is published in October and comes into force on 1 January. Some substances are banned at all times, others only in competition.